Did anyone inject it? Answers to three questions about the falsification of rabies vaccine production records for human use

  CCTV News:Following the announcement issued by National Medical Products Administration on July 15th that Changchun Changsheng Bio-freeze-dried rabies vaccine for human use was produced with false records, on the morning of 16th, Changsheng Bio-announced that all batches of freeze-dried rabies vaccine for human use were being recalled within the validity period.

 

  Changsheng Bio announced that at present, Jilin Food and Drug Administration has recovered Changchun Changsheng’s GMP Certificate, and Changchun Changsheng has stopped the production of rabies vaccine as required. All batches of products involved in this flight inspection have not yet left the factory and gone on sale, and all products have been effectively controlled. In order to ensure the safety of medication, Changchun Changsheng is recalling all batches of freeze-dried rabies vaccine for human use within the validity period. According to the monitoring of adverse reactions of the rabies vaccine by Changchun Changsheng in recent years, no adverse reactions caused by product quality problems were found.

  Changchun Changsheng will strictly implement the requirements of the regulatory authorities, actively cooperate with the regulatory authorities to carry out a comprehensive self-examination of the production and quality control system, take effective measures in time to eliminate hidden dangers in production quality, and seriously strengthen quality control.

  Changchun Changsheng deeply apologized for the occurrence of this incident. Changchun Changsheng will closely follow the progress of the incident and actively cooperate with National Medical Products Administration, Jilin Food and Drug Administration and other relevant regulatory authorities to carry out follow-up work.

  Has anyone injected the vaccine? This batch has not yet left the factory.

  For the public, the most concerned question is: has anyone injected this batch of rabies vaccine? According to the announcements made by National Medical Products Administration and the companies involved, all the products involved in this inspection have not yet left the factory and gone on sale, and all the products have been effectively controlled.

  Several major questions have attracted much attention.

  To pay attention to several major questions that have attracted much attention in this incident.

  How is fraud exposed?

  First of all: How was the vaccine problem discovered? According to the announcement issued by National Medical Products Administration on July 15th, the reason for finding the problem was "to carry out flight inspection on Changchun Changsheng according to clues".

  What is "flight inspection"

 

  Also: So what is "flight inspection"?Flight inspection is actually a surprise inspection with strong confidentiality and high efficiency. Especially for the inspection of reporting, compared with the previous follow-up inspection that notified the inspected enterprises in advance, flight inspection is a powerful means to break local protection, expose and crack down on hidden rules of the industry, and severely punish violations of laws and regulations.

  What records are fraudulent? Under investigation.

 

  The other thing is, what problems have you found?National Medical Products Administration’s notice said that it was found that the company’s production of freeze-dried rabies vaccine for human use had serious violations of the good manufacturing practice, such as falsification of records. So which records in the production process are falsified? It is still under investigation. However, at present, Jilin Food and Drug Administration has withdrawn the GMP Certificate of this enterprise, which means that the freeze-dried rabies vaccine for human use applied by this factory has been discontinued.

  At present, National Medical Products Administration has sent a special inspection team to Jilin to supervise the investigation and disposal. We will continue to pay attention to the relevant survey results.

Nanjing Mercedes-Benz EQE SUV price reduction news! The latest offer is 462,000 yuan, this time only.

[car home Nanjing Preferential Promotion Channel] At present, preferential activities are being carried out in Nanjing, with the highest preferential range reaching 30,000 yuan and the lowest starting price of 462,000 yuan. Interested friends may wish to click "Check the car price" in the quotation form and strive for higher discounts.

南京奔驰EQE

The design of Mercedes-Benz EQE SUV combines the traditional aesthetics of Mercedes-Benz family with the design concept of modern electric vehicles. The front face adopts a closed air intake grille, which is integrated with the LED headlight groups on both sides, highlighting the unique identity of the electric vehicle. The overall body lines are smooth and dynamic, with a low roof and a muscular body outline, showing a futuristic sports style. In the rear part, the taillight group adopts a unique design, which echoes the headlights and creates a strong visual impact.

南京奔驰EQE

Mercedes-Benz EQE SUV has a body size of 4880*2032*1679mm, a wheelbase of 3030mm, a front tread of 1649mm and a rear tread of 1662mm. The lines on the side of the car are smooth, with 19-inch wheels, and the tyre size is 235/55 R19, showing a luxurious and dynamic visual effect.

南京奔驰EQE

The interior design of Mercedes-Benz EQE SUV is unique, showing the perfect integration of luxury and technology. The center console is equipped with a 12.8-inch floating high-definition display screen, which integrates the control functions of multimedia system, navigation, telephone, air conditioning and skylight, and can be easily operated through voice recognition control system. The steering wheel is made of leather and equipped with electric up-and-down and forward-and-backward adjustment functions, which provides the driver with an excellent control experience. The front seats are made of imitation leather, and the main and auxiliary drivers are equipped with heating and ventilation functions, which support the adjustment of front and rear, backrest, height and leg rest, and provide four-way waist support, which brings excellent riding comfort. In addition, the driver’s seat and the co-pilot seat also have electric seat memory function, which is convenient for personalized setting. There are also USB and Type-C interfaces and wireless charging devices in the car, which meet the charging requirements of various devices.

南京奔驰EQE

Mercedes-Benz EQE SUV is equipped with an excellent motor with a maximum power of 300kW and a maximum torque of 858N·m, which brings strong power performance and smooth driving experience to drivers.

The owner of car home mentioned that although the power performance of EQE SUV is good, the low-profile model is not equipped with rear wheel steering function, which leads to a slight lack of flexibility of the vehicle. Compared with his previous BMW 3 Series, there is still a certain gap in the handling of EQE SUV. In addition, during driving, he also found that when encountering a big pit, the car body will shake more, and the suspension system is soft, which may affect the ride comfort.

Jiangxi Isuzu pickup D-MAX listed at a price of 134,000.

    [XCAR domestic new car original]

    On December 7, 2014, the high-end pickup truck D-MAX of Jiangxi Isuzu will be officially listed in Kunming, Yunnan.,The price of the new car is 134-182,800 yuan.Jiangxi ISUZU is a joint-venture vehicle manufacturer established by Japanese Isuzu in China. It is jointly funded by Japanese Isuzu and jiangling motors Group, with the equity ratio of 50:50. The domestically listed D-MAX is a new generation model.

 

Jiangxi Isuzu pickup D-MAX listed.

Jiangxi Isuzu pickup D-MAX listed at a price of 134,000.

Jiangxi Isuzu pickup D-MAX listed at a price of 134,000.

Jiangxi Isuzu pickup D-MAX listed at a price of 134,000.

Jiangxi Isuzu pickup D-MAX listed at a price of 134,000.    Speaking of the history of D-MAX, if you look at the picture below, I believe it will bring back some memories. Isuzu pickup truck began to enter China from TF model. At first, it was introduced and produced by Qingling. Later, domestic independent brands began to copy this model.

Jiangxi Isuzu 2014 D-MAX

    Appearance: more impactful than the previous generation.

    The shape design of the new generation D-MAX has a strong tough guy style. Compared with the previous generation, the new D-MAX has a more visually striking front face design. The front design is outlined by straight and angular lines. And a large number of chrome-plated decorations are applied in the middle net, and the headlights that have been rising to the side fender make it more recognizable.

Isuzu pickup D-MAX

Isuzu pickup D-MAX

    The sideways design does not have the rigid and straight lines of the previous pickup truck models. Instead, it is a more dynamic curve. For example, the rear window and the junction with the carriage and the tail are all curved strips, which inject more youthful and energetic atmosphere into the whole car. The design of the rear of the car is relatively conventional due to the limitation of the trunk. However, the chrome decoration at the rear bumper correspondingly enhances the grade sense of D-MAX.

Isuzu pickup D-MAX

Isuzu pickup D-MAX

    The external configuration of D-MAX is relatively few, but it is also normal for pickup trucks. After all, the orientation of the model does not blindly pursue high configuration, but focuses on high throughput and cargo capacity, which is reflected in its internal configuration. The front lighting uses lens halogen headlights, and the rear tail is also a halogen light source. Due to the high ground clearance, in order to facilitate passengers to get on and off, the side of the car body is also equipped with pedals. The shape of the wheel hub is simple and clear, and the off-road tires it uses are very suitable for its vehicle positioning, which greatly improves the grip of D-MAX on off road.

    Interior: The overall design is simple, clear and layered.

    Although the interior modeling of D-MAX is not so rich in design sense, it is not lacking in layering on the whole, and the regional division is clear and concise. Although the materials used are not delicate, the visual effect is not cheap. The interior does not have a complicated design language, and the overall style is simple and clear.(The picture below is taken from the D-MAX test drive of Aika in Australia, so the steering wheel is the right rudder, and the domestic model is the left rudder. The overall interior layout is basically the same as that of the Australian model.)

Jiangxi Isuzu 2014 D-MAX

Jiangxi Isuzu 2014 D-MAX    The dashboard adopts white backlight, which is clear and eye-catching. Because it is a diesel model, it will enter the red zone at 4500rpm. The center of the instrument panel is equipped with a black and white multi-function display screen. It can display many contents including mileage, fuel quantity, water temperature, fuel consumption (with instantaneous fuel consumption display) and vehicle information. The three-position steering wheel is wrapped in leather and equipped with multi-function buttons.

Jiangxi Isuzu 2014 D-MAX

Jiangxi Isuzu 2014 D-MAX

    Internal configuration is not its advantage project. As far as the positioning and service target of D-MAX are concerned, it is not difficult to understand where the focus of its models is. However, it is certainly not a problem to meet the most basic comfort of daily commuting and field work. This time, the author had the opportunity to experience the high and low models with different configurations. Compared with these two models, the biggest difference in comfort configuration lies in the multimedia entertainment system, air conditioning system and seats. Aside from these three items, the comfort configuration of the two is basically the same.

Jiangxi Isuzu 2014 D-MAX

Jiangxi Isuzu 2014 D-MAX

    Although the rear space of many pickup truck models is not the key consideration standard, the actual experience of D-MAX has not disappointed us. In the past, the experience that the rear space of pickup trucks is better than nothing will not happen on D- MAX. In terms of seat configuration, the high and low models are made of leather and fabric, and the main driver’s seat of the high model also provides electric adjustment function.

Jiangxi Isuzu 2014 D-MAX

Jiangxi Isuzu 2014 D-MAX

Jiangxi Isuzu 2014 D-MAX

Jiangxi Isuzu 2014 D-MAX

    There is plenty of storage space in the front passenger area. The glove box on the center console can be opened in two layers. And there are also cup holders at the air outlets on the left and right sides of the air conditioner, which can be used to heat or cool drinks to some extent. The front seats are equipped with central armrests, and the storage space after opening the central armrest box is considerable. The rear storage space is relatively small, and there is no rear air outlet.

Jiangxi Isuzu 2014 D-MAX

    Power: equipped with 2.5L engine and 5-speed manual/automatic manual transmission.

    Isuzu pickup truck imported from China will be equipped with 4JK1 engine, with a displacement of 2.5L, a maximum power of 136 HP and a maximum torque of 320Nm. Variable cross-section turbocharging (VGS) technology can improve the response time and acceleration ability of the engine at low speed by adjusting the exhaust flow cross-section according to the different engine speeds.

Jiangxi Isuzu 2014 D-MAX

Jiangxi Isuzu 2014 D-MAX

Jiangxi Isuzu 2014 D-MAX

    It is matched with manual and five-speed automatic manual transmission. The emission reaches the high standard of the fourth country and has the ability to upgrade to the fifth country. In terms of safety configuration, D-MAX comes standard with double airbags and early warning seat belts, which greatly improves the safety factor.

    Market prospect analysis

    In the previous test drive article, the editor of Aika Automobile once mentioned that from the perspective of head-on confrontation, there is really no pickup truck model in the domestic mid-range pickup truck market that can be similar to the comprehensive level of D-MA. However, from the positioning point of view, it seems that only Toyota’s hilux can be regarded as a competitor, but hilux’s sales volume is not good because there are fewer domestic agents and the price is slightly higher.

Jiangxi Isuzu 2014 D-MAX

    Although Zhengzhou Nissan’s D22 pickup truck is similar to D-MAX in positioning and design, the D22 model is too old to compete with D-MAX in the same generation. The Nissan Navara pickup truck, which can really compete with D-MAX, has no plans to introduce it at present.

Jiangxi Isuzu 2014 D-MAX

Jiangxi Isuzu 2014 D-MAX

    Editor’s comment:D-MAX, made in Isuzu, Jiangxi, locates high-end pickup trucks. From the previous analysis, we also see that this car has no direct competitors in China at present. However, at present, more than half of domestic consumers who buy pickup trucks are in second, third and even third-and fourth-tier cities, and most of them are mainly used for pulling goods. Therefore, pickup trucks launched by companies such as Futian and Great Wall are very popular with consumers because of their high cost performance. High-end pickup trucks like D-MAX want to open the domestic market, and the price is very important. The positioning and main attack areas should be more clearly targeted, and the best way is to do a good job in publicity.

    Review of related articles:

    Pioneer of new market Australia test drive Isuzu D-MAX

After 48 years of development, the history of Mazda 3 car series is introduced

  As a housekeeping product in the family, [Car History] has always been synonymous with sports cars. Although it seems to be extremely beautiful and brilliant now, if you know the history of Mazda 3, you will find that Mazda 3 once had an extremely difficult and bumpy development road. Now it is the time when it is listed in China. Let’s talk about the development history of Mazda 3 with you.

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The relationship between Axela/ Mazda 3 and Familia/ Mazda 323
  Naming differences between Japanese native and overseas models

  Before we know the history of Mazda 3, the editor thinks it is necessary for us to sort out some naming methods of Mazda 3, because in the development history of Mazda 3, it used many naming methods, such as Axela, Familia, Mazda 323, 00, Mazda 1000 and so on.

Mazda Mazda (import) Mazda 3 (import) 2010 hatchback 2.0 manual luxury model

Mazda 3 is called Axela』 in Japan.

  According to the custom of Mazda, a Japanese car factory, most of its cars will have two names, which are used to distinguish the domestic and export versions. Therefore, the real name of Mazda 3 should be Mazda Axela. The "3" in Mazda 3 in overseas markets is used to distinguish the physique of the vehicle, and the size of the number is directly proportional to the body shape, such as Demio, which is nicknamed Mazda 2, and Atenza, which is nicknamed Mazda 6.

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Mazda 323 (the predecessor of Mazda 3) is called Familia』 in Japan.

  Familia is actually the predecessor of Mazda 3, and it also has two names in Japan and abroad. The domestic name Familia comes from the etymology of "family" in Spanish, which means a family car with the same fun. There are many ways to name the export, such as 800, 1000, 1200, 1300, etc. At first, after the acquisition of 20% shares of Mazda in 1980, the fourth generation of Familia replaced the old way of naming the export version with Mazda 323, and in the following period, 323 became the most widely recognized name.

The first generation of Familia(1963-1968)
  Positioning small and medium-sized family cars/successfully testing water after launch

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Mazda R360』

  In the early 1960s, Mazda began to build some light cars, among which the classic Mazda R360 and Mazda 700 were born under such market conditions. Among them, Mazda R360 was born in 1960, when the price was only about 300,000 yen, and the sales volume soared after listing, and once exceeded 4,000 units in a single month. Mazda 700 was first released in 1961. It was positioned as a small and medium-sized family car, surpassing the traditional light car in all aspects, and also achieved good results in the market at that time. It is the test of these two models that laid a solid market foundation for the Familia series that will debut in the future.

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"The First Generation Familia Travel Edition"

  In October 1963, the first Mazda Familia was born, which originated from the famous Italian design -(Giorgetto Giugiaro. At first, Familia was only introduced as a commercial two-door sedan. Until April 1964, a two-door sedan based on Familia Travel Edition was officially launched. In October and November of the same year, four-door versions of Familia and Familia were also launched. At that time, the two-door Familia body design was inspired by Corvair, and the four-door model was also added with fog lights and more chrome decoration.

Remarks:Georgie Giorgetto not only designed Mazda Familia, but also designed many classic models, such as 250, bora and so on. Even the camera body of Nikon and the Apple computer were designed by him.

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"The first generation Familia four-door sedan version"

  In terms of body size, the length, width and height of Familia four-door sedan version are 3700mm/1465mm/1385mm and 2190mm respectively. The weight of the car body is only 720kg. Although it seems that the size of this car body is almost the same as that of QQ now, it really wasn’t in Japan at that time.

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"First Generation Familia Two-door Edition"

  Initially, the first generation Familia was equipped with a 0.8L four-cylinder engine with a maximum of 42 HP (31 kW) and a maximum of 59 Nm. By 1966, this engine had undergone a re-training, with a maximum power of 45 HP (33 kW) and a maximum torque of 62 Nm. In November 1965, Familia also introduced a brand-new 1.0L displacement engine model, which has a maximum power of 52 HP (38 kW) and a maximum torque of 78 Nm. It is precisely because of the different displacement that Familia was also called Mazda 800 and Mazda 1000 overseas. In addition, it is worth mentioning that the driving forms of the first generation Familia models all adopted the new layout.

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"First Generation Familia Pickup Edition"

  The first generation familia sedan version was produced until November 1967, while the travel version lasted until February 1968. In terms of sales volume, the first generation familia sold a total of 400,000 units in Japan, including overseas, of which the car version accounted for 130,000 units. At that time, the first generation of familia was not only sold locally in Japan, but also exported to Australia and some Oceania countries in New Zealand.

The Second Generation Familia(1967-1977)
  Launch a car model/start landing in the US market

  The first generation Familia, which was produced in the form of water testing, was only put into production for five years, while the second generation Familia, code-named FA3, was officially released at the end of 1967. Also on the second-generation Familia platform, a number of models have been launched, including 3-door travel version, 2-door sedan, 4-door sedan and 2-door pickup version. In terms of power, the second-generation model is still equipped with the 1.0L engine of the first-generation model.

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"The Second Generation Familia Two-door Edition"

  In terms of vehicle model changes, the overall appearance of the second-generation model has been simply redesigned, including the cancellation of the triangular window next to it, the wheelbase of the car body has increased by 40mm compared with the first-generation model, reaching 2260mm, and the headlights have also become square lights. Moreover, from the second generation model, Familia has officially started to land in the American market.

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"The Second Generation Familia Travel Edition"

  It is particularly worth mentioning that in June 1968, Mazda released a Familia equipped with a rotary engine, and the development code was "0820", which was called Familia Rotary in Japan and Mazda R100 in overseas versions. This car is based on the second generation Familia, and adopts a double-door design. The maximum power of the engine is 100 HP (74 kW) and the maximum torque is 125 Nm. However, due to the imperfect rotor engine technology at that time, the fuel consumption was extremely high and frequent failures, we had to replace it with a 1.2L inline four-cylinder TB engine with a larger exhaust capacity in September of the same year, and the overseas version was called Mazda 1200, and participated in this year’s Paris International Auto Show.

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"The second generation Familia four-door sedan version"

  On the power of the 1.2L engine launched in 1968, its maximum power reached 58 HP (43 kW) and its maximum torque reached 127 Nm. In 1970, two years after the launch of the 1.2L model, Mazda also launched a 1.3L model for Familia, with its maximum power of 69 HP (51 kW) and maximum torque of 91 Nm. When the 1.3L model was launched, the second generation Mazda had a new name: "Familia Presto". However, the overseas version still continues to use the naming method of displacement, calling it Mazda 1200 and Mazda 1300.

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"the second generation Familia four-door sedan version after the change"

  In 1973, the second generation Familia experienced a major change, and the appearance of the new car changed greatly. The engine of the previous model was continued in power, and the model code was still FA3. There are three models of 4-door /2-door /2-door coupe mainly targeted at this change, and the travel version is not among the models of the change.

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"The second generation Familia Presto』 after the change"

  Familia, after the appearance change, has a big change in the front face and a redesigned rear line. Familia continues to use the name of Familia Presto in Japan, while it is called Mazda 808 in New Zealand, Australia and other Asia-Pacific regions. However, the European region changed its name to Mazda 818 (it is said that it was renamed to 818 to avoid the similarity with the company’s naming method).

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"The tail of the second generation Familia Presto after the change"

  However, in order to cope with the automobile exhaust emission regulations promulgated in the 51st year of Showa (1976) in Japan, Familia Presto had to make a change in the same year. At the same time, the 1.0L version was cancelled in Japan, and the whole system was equipped with a 1.3L engine. Mazda named it Familia Preso 1300AP (anti-polarization), but this 1300AP only existed for one year.